Latrunculin B facilitates gravitropic curvature of Arabidopsis root by inhibiting cell elongation, especially the cells in the lower flanks of the transition and elongation zones

Plant Signal Behav. 2021 Apr 3;16(4):1876348. doi: 10.1080/15592324.2021.1876348. Epub 2021 Feb 12.

Abstract

Gravitropism plays a critical role in the growth and development of plants. Previous reports proposed that the disruption of the actin cytoskeleton resulted in enhanced gravitropism; however, the mechanism underlying these phenomena is still unclear. In the present study, real-time observation on the effect of Latrunculin B (Lat B), a depolymerizing agent of microfilament cytoskeleton, on gravitropism of the primary root of Arabidopsis was undertaken using a vertical stage microscope. The results indicated that Lat B treatment prevented the growth of root, and the growth rates of upper and lower flanks of the horizontally placed root were asymmetrically inhibited. The growth of the lower flank was influenced by Lat B more seriously, resulting in an increased differential growth rate between the upper and lower flanks of the root. Further analysis indicated that Lat B affected cell growth mainly in the transition and elongation zones. Briefly, the current data revealed that Lat B treatment inhibited cell elongation, especially the cells in the lower flanks of the transition and elongation zones, which finally manifested as the facilitation of gravitropic curvature of the primary root.

Keywords: Latrunculin B; gravitropism; growth rate; root; vertical stage microscope.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Actin Cytoskeleton / drug effects
  • Actin Cytoskeleton / metabolism
  • Arabidopsis / drug effects
  • Arabidopsis / physiology*
  • Bridged Bicyclo Compounds, Heterocyclic / pharmacology*
  • Gravitropism / drug effects*
  • Meristem / drug effects
  • Meristem / physiology
  • Plant Roots / cytology*
  • Plant Roots / drug effects
  • Plant Roots / growth & development
  • Plant Roots / physiology*
  • Thiazolidines / pharmacology*

Substances

  • Bridged Bicyclo Compounds, Heterocyclic
  • Thiazolidines
  • latrunculin B

Grants and funding

This work was supported by the National Natural Science Foundation of China [31371387]; Natural Science Foundation of Beijing Municipality [5202002].