ADHD and accidents over the life span - A systematic review

Neurosci Biobehav Rev. 2021 Jun:125:582-591. doi: 10.1016/j.neubiorev.2021.02.002. Epub 2021 Feb 11.

Abstract

Studies have demonstrated an increased risk of accidents and injuries in children, adolescents and adults with attention-deficit/hyperactivity disorder (ADHD). However, little is known about how accident risk may alter over the lifespan. Additionally, it would be important to know if the most common types of accidents and injuries differ in ADHD patients over different age groups. Furthermore, there is increasing evidence of an ameliorating effect of ADHD medication on accident risk. Lastly, the underlying risk factors and causal mechanisms behind increased accident risk remain unclear. We therefore conducted a systematic review focusing on the above described research questions. Our results suggested that accident/injury type and overall risk changes in ADHD patients over the lifespan. ADHD medication appeared to be similarly effective at reducing accident risk in all age groups. However, studies with direct comparisons of accident/injuries and effects of medication at different age groups or in old age are still missing. Finally, comorbidities associated with ADHD such as substance abuse appear to further increase the accident/injury risk.

Keywords: ADHD; Accidents; Amphetamine; Atomoxetine; Injuries; Methylphenidate; Stimulant; Trajectories.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review
  • Systematic Review

MeSH terms

  • Accidents
  • Adolescent
  • Adult
  • Attention Deficit Disorder with Hyperactivity* / drug therapy
  • Attention Deficit Disorder with Hyperactivity* / epidemiology
  • Central Nervous System Stimulants* / therapeutic use
  • Child
  • Comorbidity
  • Humans
  • Longevity
  • Methylphenidate* / therapeutic use

Substances

  • Central Nervous System Stimulants
  • Methylphenidate