Neonatal Renal Tumors

Clin Perinatol. 2021 Mar;48(1):71-81. doi: 10.1016/j.clp.2020.11.004. Epub 2021 Jan 11.


Renal tumors are rare in the neonatal period. Although some may be detected prenatally, a greater proportion present after birth, most often with a palpable abdominal mass with or without other associated symptoms. Cross-sectional imaging is typically followed by radical nephrectomy to make a specific histologic diagnosis to determine the need for additional therapy. This article reviews the clinical presentation, workup, treatment, and outcomes for neonates with some of the more common renal tumors seen in this population.

Keywords: Clear cell sarcoma of the kidney; Congenital mesoblastic nephroma; Malignant rhabdoid tumor of the kidney; Neonatal; Wilms tumor.

Publication types

  • Review

MeSH terms

  • Humans
  • Infant, Newborn
  • Kidney Neoplasms* / diagnostic imaging
  • Kidney Neoplasms* / epidemiology
  • Wilms Tumor* / diagnostic imaging
  • Wilms Tumor* / epidemiology