Prospective evaluation of the association between varicocele and benign prostatic hyperplasia in men over 40 years of age

Andrologia. 2021 May;53(4):e13933. doi: 10.1111/and.13933. Epub 2021 Feb 15.

Abstract

We investigated the association between varicocele and benign prostatic hyperplasia in men over the age of 40 years. A total of 296 outpatients were evaluated. Prostate volume was measured with transrectal ultrasound. Varicocele was diagnosed by physical examination and ultrasound. Prostatic hyperplasia was defined as prostate volume greater than or equal to 40 ml. Two groups were compared: patients with prostate volume less than 40 ml and patients with prostate volume greater than or equal to 40 ml. There was a statistically significant difference between the groups in terms of mean age, post-void residual, International Prostate Symptom Score and PSA. The percentage of patients with clinical varicocele in the group with a volume less than 40 ml and the group with a volume equal to or greater than 40 ml was 38.2% and 47.7% respectively (p = .12). There were no differences between the two groups in the percentage of patients with clinical or subclinical varicocele (43.2% vs. 52.2%, respectively, p = .12). No differences were found in the percentage of patients with varicocele when comparing men with prostates smaller than 40 ml and greater than or equal to 40 ml.

Keywords: benign prostatic hyperplasia; lower urinary tract symptoms; prostate-specific antigen; prostatic volume; total testosterone; varicocele.

MeSH terms

  • Adult
  • Humans
  • Male
  • Prospective Studies
  • Prostatic Hyperplasia* / complications
  • Prostatic Hyperplasia* / diagnostic imaging
  • Prostatic Hyperplasia* / epidemiology
  • Ultrasonography
  • Varicocele* / diagnostic imaging
  • Varicocele* / epidemiology