Ocular MRI Findings in Patients with Severe COVID-19: A Retrospective Multicenter Observational Study

Radiology. 2021 Feb 16;204394. doi: 10.1148/radiol.2021204394. Online ahead of print.


COVID-19 may affect various organs. This paper reports 9 patients (1/9 [11%] woman and 8/9 [89%] men, mean age 56 ± 13 years) with globe MRI abnormalities obtained from a multicenter cohort of 129 patients presenting with severe COVID-19 from March 4th to May 1st, 2020. 9/129 (7%) patients had one or several FLAIR-WI hyperintense nodules of the posterior pole of the globe. All patients had nodules in the macular region, 8/9 (89%) had bilateral nodules, 2/9 (22%) had nodules outside the macular region. Screening of these patients might improve the management of potentially severe ophthalmological manifestations of the virus. See also the editorial by Kirsch.

Keywords: COVID-19; MRI; Orbit; SARS-CoV-2.