Polygenic Risk Scores Predict Hypertension Onset and Cardiovascular Risk

Hypertension. 2021 Apr;77(4):1119-1127. doi: 10.1161/HYPERTENSIONAHA.120.16471. Epub 2021 Feb 22.

Abstract

[Figure: see text].

Keywords: association; blood pressure; cardiovascular diseases; genetics; hypertension; risk factors.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Blood Pressure / physiology*
  • Cardiovascular Diseases* / epidemiology
  • Cardiovascular Diseases* / genetics
  • Cardiovascular Diseases* / prevention & control
  • Female
  • Finland / epidemiology
  • Genetic Predisposition to Disease / epidemiology
  • Genome-Wide Association Study / statistics & numerical data
  • Heart Disease Risk Factors
  • Humans
  • Hypertension* / epidemiology
  • Hypertension* / genetics
  • Hypertension* / prevention & control
  • Male
  • Middle Aged
  • Multifactorial Inheritance
  • Patient-Specific Modeling
  • Predictive Value of Tests
  • Preventive Health Services / methods
  • Risk Factors