Critical Care of Patients With Cardiopulmonary Complications of Sarcoidosis

J Intensive Care Med. 2022 Apr;37(4):441-458. doi: 10.1177/0885066621993041. Epub 2021 Feb 22.


Sarcoidosis is a systemic inflammatory disease defined by the presence of aberrant granulomas affecting various organs. Due to its multisystem involvement, care of patients with established sarcoidosis becomes challenging, especially in the intensive care setting. While the lungs are typically involved, extrapulmonary manifestations also occur either concurrently or exclusively within a significant proportion of patients, complicating diagnostic and management decisions. The scope of this review is to focus on what considerations are necessary in the evaluation and management of patients with known sarcoidosis and their associated complications within a cardiopulmonary and critical care perspective.

Keywords: acute respiratory failure; cardiac rhythm disturbances; cardiac sarcoidosis; hemoptysis; pulmonary embolism; pulmonary hypertension; pulmonary infection; sarcoidosis.

Publication types

  • Review

MeSH terms

  • Critical Care
  • Granuloma / complications
  • Humans
  • Lung
  • Sarcoidosis* / complications
  • Sarcoidosis* / diagnosis
  • Sarcoidosis* / therapy