Induction of ovulation in chronically hypophysectomized Booroola ewes

J Reprod Fertil. 1988 Mar;82(2):711-5. doi: 10.1530/jrf.0.0820711.

Abstract

Booroola Merino ewes, with (F+; N = 17) and without (++; N = 13) a copy of the fecundity gene were hypophysectomized and 6 weeks later were given an i.m. injection of PMSG (high, medium or low dose) followed by hCG. The induced ovulation rates were observed laparoscopically. Ovulation rates were significantly higher (P less than 0.01) in Booroola F+ ewes than in ++ ewes (8.00 +/- 1.66 s.e.m. vs 3.62 +/- 1.10 respectively). This suggests that the high fecundity of the Booroola ewe may be due primarily to ovarian rather than pituitary factors.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chorionic Gonadotropin / pharmacology
  • Female
  • Fertility*
  • Genes
  • Gonadotropins, Equine / pharmacology
  • Hypophysectomy
  • Ovulation Induction / veterinary*
  • Pituitary Gland / physiology*
  • Sheep / physiology*

Substances

  • Chorionic Gonadotropin
  • Gonadotropins, Equine