The clinical and immunological effects of pulse methylprednisolone therapy in rheumatoid arthritis. I. Clinical effects

J Rheumatol. 1988 Feb;15(2):229-32.


The clinical effects of pulse methylprednisolone therapy were studied in 40 patients with rheumatoid arthritis. A response to pulse therapy was achieved in all but 2. The duration of response to pulse therapy alone was relatively short, but could be increased greatly by the concomitant initiation of treatment with a disease modifying agent.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arthritis, Rheumatoid / drug therapy*
  • Arthritis, Rheumatoid / immunology
  • Arthritis, Rheumatoid / physiopathology
  • Humans
  • Infusion Pumps
  • Methylprednisolone / adverse effects
  • Methylprednisolone / therapeutic use*
  • Movement / drug effects
  • Pain
  • Pulsatile Flow
  • Recurrence
  • Time Factors


  • Methylprednisolone