Abstract
This randomized clinical trial examines the superiority of a single dose of rituximab vs low-dose mycophenolate mofetil in preventing the recurrence of steroid-dependent nephrotic syndrome in children and young adults.
Trial registration:
ClinicalTrials.gov NCT04402580.
Publication types
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Randomized Controlled Trial
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Child
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Child, Preschool
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Drug Therapy, Combination
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Enzyme Inhibitors / administration & dosage*
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Female
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Humans
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Immunologic Factors / administration & dosage*
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Italy
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Male
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Mycophenolic Acid / administration & dosage*
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Nephrotic Syndrome / drug therapy*
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Recurrence
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Remission Induction
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Risk
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Rituximab / administration & dosage*
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Steroids / administration & dosage
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Young Adult
Substances
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Enzyme Inhibitors
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Immunologic Factors
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Steroids
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Rituximab
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Mycophenolic Acid
Associated data
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ClinicalTrials.gov/NCT04402580