Risk Factors Associated With Complications After Unilateral Immediate Breast Reconstruction: A French Prospective Multicenter Study

In Vivo. 2021 Mar-Apr;35(2):937-945. doi: 10.21873/invivo.12334.

Abstract

Background/aim: For women who have undergone a mastectomy, breast reconstruction provides psychological as well as aesthetic benefits. Thus, many patients ask for an immediate breast reconstruction (IBR). The present study focuses on risk factors assiociated with complications after IBR.

Patients and methods: A national prospective study (2007-2009) was conducted on 404 patients who underwent an unilateral IBR: 205 implants alone (IA) including 46 tissue expanders, 91 latissimus dorsi musculocutaneous flaps with implant (LDI), 78 autologous latissimus dorsi musculocutaneous flaps (LD), and 30 autologous transverse rectus abdominis musculocutaneous flaps (TRAM). Outcomes concerned major and minor complications, as well as early and late complications.

Results: Related risks of complications were different according to the IBR technique. Major complications rate remained moderate and concerned 15% of patients. Obesity and diabetes significantly increased the incidence of major complications.

Conclusion: To reduce complication rate, the risk factors associated with each type of IBR should be taken into account.

Keywords: Breast cancer; breast reconstruction; complications; mastectomy; morbidity; risk factors.

Publication types

  • Multicenter Study

MeSH terms

  • Breast Neoplasms* / epidemiology
  • Breast Neoplasms* / surgery
  • Female
  • Humans
  • Mammaplasty* / adverse effects
  • Mastectomy / adverse effects
  • Postoperative Complications / epidemiology
  • Postoperative Complications / etiology
  • Prospective Studies
  • Retrospective Studies
  • Risk Factors