The Advantage of Pinpoint Camera System With Indocyanine Green for Sentinel Lymph Node Micrometastasis Detection in Low Risk Endometrial Cancer

In Vivo. 2021 Mar-Apr;35(2):1033-1039. doi: 10.21873/invivo.12347.

Abstract

Background/aim: This report outlines our experience in the management of 10 cases of low-risk endometrial cancer with Indocyanine Green for sentinel lymph node (SLN) mapping using the Pinpoint 30-degree 4K S1 SPY real-time camera system (Stryker). This system offers simultaneous, real-time, high-definition white light and fluorescence imaging through a single laparoscope, without the need to change camera filters.

Patients and methods: In our retrospective case series we included all endometrioid endometrial cancers of grade G1 and pre-operative radiological staging FIGO 1A reported on magnetic resonance imaging (MRI) that were treated laparoscopically from October 2019 to April 2020.

Results: Bilateral sentinel lymph node excision was achieved in 9 out of 10 cases. In one patient, one sentinel lymph node featuring a micrometastasis of <2 mm was identified.

Conclusion: A specialist minimal access team can safely and reliably reproduce this technique for sentinel lymph node excision.

Keywords: Endometrial cancer; PinPoint camera system; indocyanine green; laparoscopy; lymphadenectomy; sentinel lymph node.

MeSH terms

  • Coloring Agents
  • Endometrial Neoplasms* / diagnostic imaging
  • Endometrial Neoplasms* / surgery
  • Female
  • Humans
  • Indocyanine Green
  • Lymph Node Excision
  • Lymph Nodes / pathology
  • Neoplasm Micrometastasis / diagnosis
  • Neoplasm Staging
  • Retrospective Studies
  • Sentinel Lymph Node Biopsy
  • Sentinel Lymph Node* / diagnostic imaging
  • Sentinel Lymph Node* / surgery

Substances

  • Coloring Agents
  • Indocyanine Green