Prevention of Pruritis following Spinal Morphine for Scheduled Cesarean Birth

MCN Am J Matern Child Nurs. 2021 Mar-Apr;46(2):97-102. doi: 10.1097/NMC.0000000000000693.

Abstract

Background: Intrathecal morphine provides effective analgesia after cesarean birth, yet up to 90% of women who receive it experience excessive itching, an undesirable dose-dependent effect. Pruritis may increase nursing workload, delay breastfeeding, and decrease patient satisfaction. When 0.1 mg spinal morphine is given, pruritis is markedly reduced while analgesia is preserved.

Purpose: The purpose of this project was to determine possible causes and solutions for pruritus after cesarean birth.

Methods: Anesthesia providers were educated and encouraged to limit spinal morphine to 0.1 mg as a strategy to prevent pruritus. In a repeated measures design, the rate of treatment-required pruritus and opioid consumption were measured 24 hours after surgery. The project included an evaluation of 30 medical records before and 30 medical records after the project intervention.

Results: Preintervention rate of treatment-required pruritis was 37%, all received spinal morphine ≥ 1.5 mg. Postintervention rate of treatment-required pruritis was 13% and 57% after spinal morphine 0.1 mg and 0.2 mg, respectively. Opioid consumption was similar between groups.

Clinical implications: Mother-baby nurses can have an impact on the practice of anesthesia providers by advocating for evidence-based dosing of intrathecal morphine to reduce the incidence of pruritis while maintaining effective analgesia for women after cesarean birth.

MeSH terms

  • Adult
  • Analgesics, Opioid / administration & dosage
  • Analgesics, Opioid / adverse effects
  • Cesarean Section / adverse effects*
  • Cesarean Section / methods
  • Female
  • Hospitals, Military / organization & administration
  • Hospitals, Military / statistics & numerical data
  • Humans
  • Injections, Epidural / methods
  • Injections, Epidural / standards
  • Injections, Epidural / statistics & numerical data
  • Morphine / administration & dosage
  • Morphine / adverse effects*
  • Pain Management / adverse effects
  • Pain Management / methods
  • Pain Management / statistics & numerical data
  • Pain Measurement / methods
  • Pain Measurement / statistics & numerical data
  • Pruritus / prevention & control*
  • Retrospective Studies

Substances

  • Analgesics, Opioid
  • Morphine