Recent Progress of Novel Electrochemiluminescence Nanoprobes and Their Analytical Applications

Shiyu Zhang; Yang Liu

doi:10.3389/fchem.2020.626243

Recent Progress of Novel Electrochemiluminescence Nanoprobes and Their Analytical Applications

Front Chem. 2021 Feb 9:8:626243. doi: 10.3389/fchem.2020.626243. eCollection 2020.

Authors

Shiyu Zhang¹, Yang Liu¹

Affiliation

¹ Department of Chemistry, Beijing Key Laboratory for Analytical Methods and Instrumentation, Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology of Ministry of Education, Tsinghua University, Beijing, China.

Abstract

High-performance nanomaterials have been seen as a new generation of electrochemiluminescence (ECL) probes or emitters for their finely tunable structure and concomitant remarkable properties, guaranteeing the prospective applications in the analysis and diagnosis devices with superior performances. The structure-activity relationships of ECL nanoprobes in nanoscale are presenting milestone in understanding of the ECL microscopic behaviors and mechanisms, and guide the exploitation of novel ECL probes. In this mini-review, we summarized the recent development of novel ECL probes based on the nanomaterials. The mechanism and relationships between their structure as well as the active sites and functionality were revealed. In addition, the design and regulation of the ECL nanoprobes were emphasized for the biosensing and imaging application. Finally, the potential prospect of the ECL nanoprobes, design, and their applications were discussed.

Keywords: biosensing; electrochemiluminescence; imaging; nanomaterials; structure-properties relationship.

Publication types

Review