Tumor Microenvironment and the Role of Artificial Intelligence in Breast Cancer Detection and Prognosis

Am J Pathol. 2021 Aug;191(8):1364-1373. doi: 10.1016/j.ajpath.2021.01.014. Epub 2021 Feb 24.

Abstract

A critical knowledge gap has been noted in breast cancer detection, prognosis, and evaluation between tumor microenvironment and associated neoplasm. Artificial intelligence (AI) has multiple subsets or methods for data extraction and evaluation, including artificial neural networking, which allows computational foundations, similar to neurons, to make connections and new neural pathways during data set training. Deep machine learning and AI hold great potential to accurately assess tumor microenvironment models employing vast data management techniques. Despite the significant potential AI holds, there is still much debate surrounding the appropriate and ethical curation of medical data from picture archiving and communication systems. AI output's clinical significance depends on its human predecessor's data training sets. Integration between biomarkers, risk factors, and imaging data will allow the best predictor models for patient-based outcomes.

Publication types

  • Review

MeSH terms

  • Artificial Intelligence*
  • Breast Neoplasms / diagnosis*
  • Breast Neoplasms / pathology*
  • Female
  • Humans
  • Prognosis
  • Tumor Microenvironment*