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Review
. 2021 Feb 11:8:590578.
doi: 10.3389/fped.2020.590578. eCollection 2020.

Management of Patent Ductus Arteriosus in Premature Infants in 2020

Sarah Parkerson  1 , Ranjit Philip  2 , Ajay Talati  3 , Shyam Sathanandam  2
Affiliations
Review

Management of Patent Ductus Arteriosus in Premature Infants in 2020

Sarah Parkerson et al. Front Pediatr. .

Abstract

The patent ductus arteriosus (PDA) is the most commonly found cardiac condition in neonates. While there have been several studies and thousands of publications on the topic, the decision to treat the PDA is still strongly debated among cardiologists, surgeons, and neonatologists. This is in part due to the shortage of long-term benefits with the interventions studied. Practice variations still exist within sub-specialties and centers. This article briefly summarizes the history, embryology and histology of the PDA. It also succinctly discusses the hemodynamic significance of a PDA which builds the framework to review all the available literature on PDA closure in premature infants, though not a paradigm shift just yet; it introduces transcatheter PDA closure (TCPC) as a possible armament to the clinician for this age-old problem.

Keywords: PDA; patent ductus arteriosus (patent arterial duct); prematurity and low birth weight; surgical ligation of patent ductus arteriosus; transcatheter ductus closure.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
(A) Transthoracic Echocardiogram (parasternal short axis image with color Doppler) demonstrating the relative size of the patent ductus arteriosus (PDA) in comparison to the left pulmonary artery (LPA) and right pulmonary artery (RPA). (B) Post-transcatheter PDA closure.
Figure 2
Figure 2
Transthoracic Apical 4-chamber view showing left atrial and ventricular dilation suggestive of a hemodynamically significant PDA.
Figure 3
Figure 3
Abdominal Aorta Doppler pattern showing diastolic flow reversal indicative of a hemodynamically significant PDA.
See this image and copyright information in PMC

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