Ivabradine and Blood Pressure Reduction: Underlying Pleiotropic Mechanisms and Clinical Implications

Front Cardiovasc Med. 2021 Feb 10:8:607998. doi: 10.3389/fcvm.2021.607998. eCollection 2021.

Fedor Simko^{1

2

3}, Tomas Baka¹

¹ Institute of Pathophysiology, Faculty of Medicine, Comenius University, Bratislava, Slovakia.
² 3rd Department of Internal Medicine, Faculty of Medicine, Comenius University, Bratislava, Slovakia.
³ Institute of Experimental Endocrinology, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia.

No abstract available

Keywords: blood pressure; endothelial dysfunction; ivabradine; neurohumoral activation; vascular stiffness.