Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Jul 1;181(7):992-994.
doi: 10.1001/jamainternmed.2021.0022.

Glycemic Control and Use of High-risk Antihyperglycemic Agents Among Nursing Home Residents With Diabetes in Ontario, Canada

Iliana C Lega  1   2   3 , Michael A Campitelli  3 , Jeremy Matlow  1   2 , Yingbo Na  1   3 , Nathan M Stall  1   2   4 , Paula A Rochon  1   2   3   4 , Lorraine L Lipscombe  1   2   3
Affiliations

Glycemic Control and Use of High-risk Antihyperglycemic Agents Among Nursing Home Residents With Diabetes in Ontario, Canada

Iliana C Lega et al. JAMA Intern Med. .

Abstract

This cohort study examines levels of glycemic control among nursing home residents with diabetes and compares rates of intensive glycemic control with high-risk antihyperglycemic agents across levels of cognitive impairment.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest Disclosures: None reported.

Figures

Figure.
Figure.. Mean Glycated Hemoglobin (HbA1c) Levels Among Residents Treated With High-risk Antihyperglycemic Agents by Degree of Cognitive Impairment (CI)
Mean HbA1c levels among nursing home residents treated with high-risk antihyperglycemic agents were compared among levels of cognitive impairment. Mean HbA1c was categorized as: HbA1c of 7.0% or lower, 7.1% to 8.5%, higher than 8.5%. Cognitive status was determined using the validated MDS Cognitive Performance Scale and residents were classified as follows: intact/borderline impairment, 0-1; mild/moderate impairment, 2 to 3; severe impairment 4 or higher. Among residents treated with high-risk antihyperglycemic agents (n = 7479), those with severe cognitive impairment were significantly more likely to be treated to intensive glycemic targets (HbA1c <7%) compared with residents with mild/moderate cognitive impairment (44.7% vs 39.3%, P = .01) and intact/borderline cognitive impairment (44.7% vs 38.4%, P = .004).
See this image and copyright information in PMC

Comment in

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Lipska KJ, Ross JS, Miao Y, Shah ND, Lee SJ, Steinman MA. Potential overtreatment of diabetes mellitus in older adults with tight glycemic control. JAMA Intern Med. 2015;175(3):356-362. doi:10.1001/jamainternmed.2014.7345 - DOI - PMC - PubMed
    1. American Diabetes Association . 12. Older Adults: Standards of Medical Care in Diabetes-2019. Diabetes Care. 2019;42(suppl 1):S139-S147. doi:10.2337/dc19-S012 - DOI - PubMed
    1. Society AG. Ten Things Clinicians and Patients Should Question. Published 2019. Accessed October 26, 2020. https://www.choosingwisely.org/societies/american-geriatrics-society/
    1. Hux JE, Ivis F, Flintoft V, Bica A. Diabetes in Ontario: determination of prevalence and incidence using a validated administrative data algorithm. Diabetes Care. 2002;25(3):512-516. doi:10.2337/diacare.25.3.512 - DOI - PubMed
    1. Morris JN, Fries BE, Mehr DR, et al. . MDS Cognitive Performance Scale. J Gerontol. 1994;49(4):M174-M182. doi:10.1093/geronj/49.4.M174 - DOI - PubMed

Publication types