Specificity of International Classification of Diseases codes for bronchopulmonary dysplasia: an investigation using electronic health record data and a large insurance database

J Perinatol. 2021 Apr;41(4):764-771. doi: 10.1038/s41372-021-00965-3. Epub 2021 Mar 1.

Abstract

Objective: International Classification of Diseases (ICD) codes in electronic health records (EHRs) are increasingly used for health services research, in spite of unknown diagnostic accuracy. The accuracy of ICD codes to identify bronchopulmonary dysplasia (BPD) is unknown.

Study design: Retrospective cohort study in a single-center NICU (n = 166) to evaluate sensitivity and specificity of ICD-10 codes for the diagnosis of BPD. Analysis of large insurance claims database (n = 7887) to determine date of assignment of the code.

Results: The sensitivity of any BPD-related ICD codes ranged from 0.82 to 0.95, while the specificity ranged from 0.25 to 0.36. In a large national insurance database, the most common date of ICD-9 or ICD-10 code assignment was the day of birth, which is inconsistent with the clinical definition.

Conclusions: ICD codes registered for BPD are unlikely to accurately reflect the current clinical definition and should be interpreted with caution.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Bronchopulmonary Dysplasia* / diagnosis
  • Bronchopulmonary Dysplasia* / epidemiology
  • Electronic Health Records
  • Humans
  • Infant, Newborn
  • Insurance*
  • International Classification of Diseases
  • Retrospective Studies