Irreversible Electroporation of Recurrent Hepatocellular Carcinoma After Liver Transplantation: Report of Two Cases

Cardiovasc Intervent Radiol. 2021 May;44(5):807-811. doi: 10.1007/s00270-021-02784-7. Epub 2021 Mar 2.


The treatment strategies of post-transplant hepatocellular carcinoma (HCC) recurrence have not been completely clarified. Thermal ablative techniques have been increasingly performed for the treatment of post-transplant HCC recurrences. However, thermal ablation can create abnormal communication with the biliary tract and the ablation site by causing biliary injury. This abnormal communication may cause bacterial contamination and abscess formation. Irreversible electroporation (IRE) is a nonthermal ablative technique which may reduce the risk of abscess development at the ablation site due to its low risk of thermal injury to the biliary system. IRE may also preserve the perilesional blood vessels. This report describes two cases of post-transplant intrahepatic HCC recurrence which were successfully treated with IRE.

Keywords: Hepatocellular carcinoma; Irreversible electroporation; Liver transplantation; Recurrent.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Carcinoma, Hepatocellular / diagnosis
  • Carcinoma, Hepatocellular / therapy*
  • Electroporation / methods*
  • Humans
  • Liver Neoplasms / diagnosis
  • Liver Neoplasms / therapy*
  • Liver Transplantation / adverse effects*
  • Magnetic Resonance Imaging
  • Male