Air pollution exposure-the (in)visible risk factor for respiratory diseases

Environ Sci Pollut Res Int. 2021 Apr;28(16):19615-19628. doi: 10.1007/s11356-021-13208-x. Epub 2021 Mar 4.

Abstract

There is increasing interest in understanding the role of air pollution as one of the greatest threats to human health worldwide. Nine of 10 individuals breathe air with polluted compounds that have a great impact on lung tissue. The nature of the relationship is complex, and new or updated data are constantly being reported in the literature. The goal of our review was to summarize the most important air pollutants and their impact on the main respiratory diseases (chronic obstructive pulmonary disease, asthma, lung cancer, idiopathic pulmonary fibrosis, respiratory infections, bronchiectasis, tuberculosis) to reduce both short- and the long-term exposure consequences. We considered the most important air pollutants, including sulfur dioxide, nitrogen dioxide, carbon monoxide, volatile organic compounds, ozone, particulate matter and biomass smoke, and observed their impact on pulmonary pathologies. We focused on respiratory pathologies, because air pollution potentiates the increase in respiratory diseases, and the evidence that air pollutants have a detrimental effect is growing. It is imperative to constantly improve policy initiatives on air quality in both high- and low-income countries.

Keywords: Air pollution; Asthma; Chronic obstructive pulmonary disease; Exposure; Lung cancer; Particulate matter; Respiratory diseases.

Publication types

  • Review

MeSH terms

  • Air Pollutants* / analysis
  • Air Pollution* / adverse effects
  • Air Pollution* / analysis
  • Environmental Exposure / analysis
  • Humans
  • Nitrogen Dioxide / analysis
  • Ozone* / analysis
  • Particulate Matter / analysis
  • Risk Factors
  • Sulfur Dioxide

Substances

  • Air Pollutants
  • Particulate Matter
  • Sulfur Dioxide
  • Ozone
  • Nitrogen Dioxide