Spinal Cord Compression as a Consequence of Spinal Plasmacytoma in a Patient with Multiple Myeloma: A Case Report

Clin Pract. 2021 Feb 25;11(1):124-130. doi: 10.3390/clinpract11010018.


Multiple myeloma (MM) is a B cell malignancy resulting in osteolytic lesions. Pathological fracture of the vertebral body resulting in spinal cord compression is a common complication and accounts for approximately 5% of patients with MM. To date, there are no definitive guidelines for the treatment of spinal cord compression as a consequence of MM. Radiotherapy has frequently been the preferred form of treatment. Some surgeons, however, feel that spinal lesions in multiple myeloma should be treated in the same manner as spinal metastases from solid organs. I report the management of a 46-year-old gentleman with multiple myeloma that had resulted in neural compression in the lumbar and thoracic areas. Initial emergent treatment in this patient consisted of spinal decompression and stabilisation.

Keywords: metastatic spinal cord compression; multiple myeloma (MM); spinal decompression; spinal stabilisation.

Publication types

  • Case Reports