A novel non-enzymatic glucose sensor based on NiFe(NPs)-polyaniline hybrid materials

Delloula Lakhdari; Abderrahim Guittoum; Nassima Benbrahim; Ouafia Belgherbi; Mohammed Berkani; Yasser Vasseghian; Nadjem Lakhdari

doi:10.1016/j.fct.2021.112099

A novel non-enzymatic glucose sensor based on NiFe(NPs)-polyaniline hybrid materials

Food Chem Toxicol. 2021 May:151:112099. doi: 10.1016/j.fct.2021.112099. Epub 2021 Mar 4.

Authors

Delloula Lakhdari¹, Abderrahim Guittoum², Nassima Benbrahim³, Ouafia Belgherbi⁴, Mohammed Berkani⁵, Yasser Vasseghian⁶, Nadjem Lakhdari⁷

Affiliations

¹ Research Center in Industrial Technologies CRTI, P.O. Box 64, Cheraga, 16014, Algiers, Algeria; Laboratoire de Physique et Chimie des Matériaux (LPCM), Université Mouloud Mammeri de Tizi-Ouzou, RP 15000, Algeria. Electronic address: d.lakhdari@crti.dz.
² Nuclear Research Centre of Algiers, 2 Bd Frantz Fanon, Bp 399, Alger-Gare, Algiers, Algeria.
³ Laboratoire de Physique et Chimie des Matériaux (LPCM), Université Mouloud Mammeri de Tizi-Ouzou, RP 15000, Algeria.
⁴ Research Center in Industrial Technologies CRTI, P.O. Box 64, Cheraga, 16014, Algiers, Algeria.
⁵ Laboratoire Biotechnologies, Ecole Nationale Supérieure de Biotechnologie, Ville Universitaire Ali Mendjeli, BP E66 25100, Constantine, Algeria. Electronic address: m.berkani@ensbiotech.edu.dz.
⁶ Center for Advanced Chemistry, Institute of Research and Development, Duy Tan University, 03 Quang Trung, Da Nang 550000, Vietnam; The Faculty of Environmental and Chemical Engineering, Duy Tan University, 03 Quang Trung, Da Nang 550000, Vietnam. Electronic address: yasservasseghian@duytan.edu.vn.
⁷ Laboratoire Biotechnologies, Ecole Nationale Supérieure de Biotechnologie, Ville Universitaire Ali Mendjeli, BP E66 25100, Constantine, Algeria. Electronic address: n.lakhdari@ensbiotech.edu.dz.

PMID: 33677039
DOI: 10.1016/j.fct.2021.112099

Abstract

This article was focused on the elaboration of NiFe-Polyaniline glucose sensors via electrochemical technique. Firstly, the PANi (polyaniline) fibers were synthesized by oxidation of the monomer aniline on FTO (fluorine tin oxide) substrate. Secondly, the Nickel-Iron nanoparticles (NiFe (NPs)) were obtained by the Chronoamperometry method on the Polyaniline surface. The NiFe-PANi hybrid electrode was characterized by scanning electron microscopy (SEM), force atomic microscopy (AFM), Fourier-transformed infrared (FTIR), and X-ray diffraction (XRD). The electrochemical glucose sensing performance of the NiFe alloy nanoparticle was studied by cyclic voltammetry and amperometry. The fabricated glucose sensor Ni-Fe hybrid material exhibited many remarkable sensing performances, such as low-response time (4 s), sensitivity (1050 μA mM^-1 cm^-2), broad linear range (from 10 μM -1 mM), and low limit of detection (LOD) (0.5 μM, S/N = 3). The selectivity, reliability, and stability of the NiFe hybrid material for glucose oxidation were also investigated. All the results demonstrated that the NiFe-PANi/FTO hybrid electrode is very promising for application in electrochemical glucose sensing.

Keywords: Glucose; NiFe nanoparticles; Non-enzymatic sensor; Polyaniline; Reliability; Selectivity.

MeSH terms

Aniline Compounds / chemistry*
Biosensing Techniques / instrumentation*
Electrochemical Techniques / methods
Glucose / analysis*
Iron / chemistry*
Limit of Detection
Metal Nanoparticles / chemistry*
Microscopy, Atomic Force
Microscopy, Electron, Scanning
Nickel / chemistry*
Reproducibility of Results
Spectroscopy, Fourier Transform Infrared
X-Ray Diffraction

Substances

Aniline Compounds
polyaniline
Nickel
Iron
Glucose