Supraclavicular lymphadenopathy following COVID-19 vaccination: an increasing presentation to the two-week wait neck lump clinic?

Br J Oral Maxillofac Surg. 2021 Apr;59(3):384-385. doi: 10.1016/j.bjoms.2021.02.002. Epub 2021 Feb 15.


The first COVID-19 vaccination was given in December 2020 and there is an effort to vaccinate the international population on a massive scale. Common side effects from the vaccine include headache and tiredness. Regional lymphadenopathy has been described in relation to other vaccines. We describe two cases of supraclavicular reactive lymphadenopathy presenting in patients who had the COVID vaccination in the ipsilateral arm. Awareness of this diagnosis is important for patients presenting to the neck lump clinic.

Keywords: COVID-19; lymphadenopathy; neck lump.

MeSH terms

  • COVID-19 Vaccines
  • COVID-19*
  • Humans
  • Lymphadenopathy* / etiology
  • SARS-CoV-2
  • Vaccination / adverse effects


  • COVID-19 Vaccines