The role of antibiotics in the surgical management of paediatric obstructive sleep apnoea (OSA): a cohort study

Eur Arch Otorhinolaryngol. 2021 Dec;278(12):5077-5080. doi: 10.1007/s00405-021-06720-w. Epub 2021 Mar 9.

Abstract

Purpose: Obstructive sleep apnoea (OSA) describes an irregular night-time breathing pattern that is present in approximately 1.8% of children and can have a negative impact on quality of life. The use of antibiotics postoperatively is controversial. They are commonly prescribed; however, they can also be associated with side effects and resistance. This study explores the role of antibiotics in the post-operative management of children with OSA in a cohort of children.

Methods: We conducted a retrospective cohort study of children undergoing surgery for OSA or sleep disordered breathing (SDB) at a tertiary paediatric ENT referral centre from November 2018 to November 2019.

Results: This study identified 382 children who had undergone surgical treatment for OSA or sleep disordered breathing (SDB); 319 underwent adenotonsillectomy, 53 adenoidectomy and 10 tonsillectomies. Antibiotics were given post-operatively to 158 (41%) patients and 18 (11%) of these patients presented to hospital with post-operative complications. A higher number of patients re-presented to hospital from the group who did not receive antibiotics (p = 0.982). Bleeding (p = 0.886) and infection (p = 0.823) were also more common in those children who did not receive antibiotics.

Conclusion: Antibiotics led to fewer complications and re-presentations to hospital in children undergoing operative management of OSA; however, this trend was not found to be statistically significant.

Keywords: Adenotonsillectomy; Analgesia; Antibiotics; OSA; Post-operative; SDB.

MeSH terms

  • Adenoidectomy
  • Anti-Bacterial Agents / therapeutic use
  • Child
  • Cohort Studies
  • Humans
  • Quality of Life
  • Retrospective Studies
  • Sleep Apnea, Obstructive* / surgery
  • Tonsillectomy*

Substances

  • Anti-Bacterial Agents