Is it Possible to Estimate the Bioequivalence between Parenteral and Enteral Formulations of Escin?

Curr Rev Clin Exp Pharmacol. 2022;17(2):82-84. doi: 10.2174/1574884716666210309103109.

Luca Gallelli^{1

2}, Erika Cione³, Leiming Zhang⁴, Tian Wang⁴

¹ Department of Health Science, School of Medicine, University Magna Graecia of Catanzaro, Operative Unit of Clinical Pharmacology, Mater Domini University Hospital, Catanzaro, Italy.
² Research Center FAS@UMG, University Magna Graecia of Catanzaro, Italy.
³ Department of Pharmacy, Health and Nutritional Sciences, Department of Excellence 2018-2022, University of Calabria, 87036 Rende (CS), Italy.
⁴ Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, School of Pharmacy, Yantai University, Yantai, 264005, China.

Abstract

We suggest that enteral formulation of escin could be used instead of enteral formulation if it is not available.

Keywords: Escin; edema; enteral formulation; parenteral formulation; vascular.