Diagnosis & management of imported malaria in pregnant women in non-endemic countries

Indian J Med Res. 2020 Nov;152(5):449-455. doi: 10.4103/ijmr.IJMR_851_18.

Abstract

Malaria in pregnancy is an important cause of maternal and foetal morbidity and is a potentially life-threatening infection. With ever-growing global exchanges, imported malaria in pregnancy is becoming an issue of concern in non-endemic countries where women, because of low immunity, have higher risk of severe diseases and death. Malaria in pregnancy is a dangerous condition which can be associated with important consequences for both mother and child such as stillbirth, low birth weight, maternal anaemia. In non-endemic-countries it is more frequent in its severe form which can lead to maternal death if not treated adequately. Specific anti-malarial interventions such as the use of repellents and insecticide treated bed nets in addition to chemoprophylaxis should be used by pregnant women if they are travelling to endemic areas. In cases of confirmed infection, specific treatment regimens vary according to gestational age and the presence of complications. Malaria should be considered a global health problem, increasingly involving western countries. Clinicians all over the world need to be prepared for this emerging disease both in terms of prevention and therapy.

Keywords: Malaria; Plasmodium falciparum; placental malaria; pregnancy; prevention; severe malaria; travel.

Publication types

  • Review

MeSH terms

  • Antimalarials* / therapeutic use
  • Child
  • Female
  • Humans
  • Infant, Newborn
  • Malaria* / diagnosis
  • Malaria* / drug therapy
  • Malaria* / epidemiology
  • Malaria, Falciparum* / drug therapy
  • Pregnancy
  • Pregnancy Complications, Infectious* / drug therapy
  • Pregnant Women
  • Travel

Substances

  • Antimalarials