Risk stratification for venous thrombosis in post-partum women in a tertiary care setup in south India

Indian J Med Res. 2020 Nov;152(5):523-526. doi: 10.4103/ijmr.IJMR_1564_18.

Abstract

Background & objectives: The Royal College of Obstetricians and Gynaecologists (RCOG) guidelines for thromboprophylaxis among post-partum women are recommended across Asia. This study was aimed to find the proportion of post-partum women eligible for thromboprophylaxis based on the RCOG guidelines and how many actually received it in a tertiary care health facility in south India.

Methods: This cross-sectional study was carried out on 1652 consecutive women who delivered in the setup of tertiary care. Risk stratification for venous thrombosis was done as per the RCOG guidelines. The number of women who received thromboprophylaxis was also noted.

Results: Among the 1652 women studied, three [0.18%; 95% confidence interval (CI): 0.06-0.53] were in the high-risk, 598 (36.2%; 95% CI: 33.9-38.6) in the intermediate and 254 (15.4%; 95% CI: 13.7-17.2) in the low-risk category for thrombosis. All the three women in the high-risk and only two women in the intermediate-risk category actually received thromboprophylaxis with heparin.

Interpretation & conclusions: It was seen that the number of women needing prophylaxis in our setup, as per the RCOG guidelines, was as high as 601 (36.4%), but only five (0.8%) received it.

Keywords: Post-partum thrombosis; thromboprophylaxis; thrombosis risk; venous thrombosis.

MeSH terms

  • Anticoagulants
  • Asia
  • Cross-Sectional Studies
  • Female
  • Heparin, Low-Molecular-Weight / therapeutic use
  • Humans
  • India / epidemiology
  • Postpartum Period
  • Risk Assessment
  • Tertiary Healthcare
  • Venous Thromboembolism*
  • Venous Thrombosis* / epidemiology

Substances

  • Anticoagulants
  • Heparin, Low-Molecular-Weight