Minimally invasive video-assisted parathyroidectomy (MIVAP) without intraoperative PTH determination

Eur Arch Otorhinolaryngol. 2021 Dec;278(12):4997-5001. doi: 10.1007/s00405-021-06740-6. Epub 2021 Mar 13.

Abstract

Background: Minimally invasive video-assisted parathyroidectomy (MIVAP) has become a standard approach to primary hyperparathyroidism (pHPT) since described. Although intraoperative parathyroid hormone assay (IOPTH) has been generalized as a complementary technique to MIVAP, its actual impact on the surgical success of this technique is not without controversy. The aim of this study was to describe our results in the management of pHPT with successful preoperative localization, by MIVAP technique, without IOPTH determination, confirming in a larger series our preliminary results.

Methods: A retrospective descriptive study was conducted in pHPT patients treated by MIVAP with no IOPTH determination in a tertiary hospital between 2007 and 2019.

Results: A total of 167 patients were included in the study. Biochemical cure was achieved in 96.4%, and 94.1% did not present any surgical complication. The mean duration of surgery was 61 min, and the mean length of hospital stay was 1.8 days CONCLUSIONS: In case of positive preoperative localization studies, MIVAP is a safe and effective technique for the surgical treatment of pHPT due to a parathyroid adenoma, regardless of IOPTH determination, with a success rate > 95% and a low complication rate.

Keywords: IOPTH; MIVAP; PTH; Primary hyperparathyroidism.

MeSH terms

  • Humans
  • Hyperparathyroidism, Primary* / diagnosis
  • Hyperparathyroidism, Primary* / surgery
  • Minimally Invasive Surgical Procedures
  • Parathyroid Hormone
  • Parathyroidectomy*
  • Retrospective Studies
  • Video-Assisted Surgery

Substances

  • Parathyroid Hormone