Immunogenicity of a Single Dose of SARS-CoV-2 Messenger RNA Vaccine in Solid Organ Transplant Recipients

JAMA. 2021 May 4;325(17):1784-1786. doi: 10.1001/jama.2021.4385.

Abstract

This study quantifies antispike protein antibody responses to first-dose messenger RNA (mRNA) COVID-19 vaccines in solid organ transplant recipients to better understand the immunogenicity of the vaccines in immunocompromised individuals.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Aged
  • Antibodies, Viral / blood*
  • COVID-19 / immunology
  • COVID-19 / prevention & control*
  • COVID-19 Vaccines / immunology*
  • Female
  • Humans
  • Immunoenzyme Techniques
  • Immunogenicity, Vaccine*
  • Male
  • Middle Aged
  • Organ Transplantation
  • Prospective Studies
  • Spike Glycoprotein, Coronavirus / immunology*
  • Transplant Recipients*
  • Vaccines, Synthetic / immunology
  • mRNA Vaccines

Substances

  • Antibodies, Viral
  • COVID-19 Vaccines
  • Spike Glycoprotein, Coronavirus
  • Vaccines, Synthetic
  • spike protein, SARS-CoV-2