Comprehensive review of imaging features of sex cord-stromal tumors of the ovary

Abdom Radiol (NY). 2021 Apr;46(4):1519-1529. doi: 10.1007/s00261-021-02998-w. Epub 2021 Mar 16.


Sex cord-stromal tumors of the ovary (SCST) are uncommon ovarian tumors arising from sex cord and/or stromal cells of the ovaries. They may be nonfunctional and asymptomatic or functional presenting with hyperestrogenic, hyperandrogenic or cushingoid symptoms. They present in a wide age group of women, mostly in early stages and follow a nonaggressive clinical course after surgical resection. They differ from more prevalent epithelial ovarian tumors which tend to present in older women in advanced stages with poor prognosis. Some of SCSTs are associated with clinical syndromes. We will review imaging features on ultrasound, computed tomography and magnetic resonance imaging, epidemiology and clinical presentations of these tumors.

Keywords: Fibroma; Granulosa cell tumor; Sertoli cell tumor; Sex cord-stromal tumors of the ovary; Thecoma.

Publication types

  • Review

MeSH terms

  • Aged
  • Female
  • Humans
  • Ovarian Neoplasms* / diagnostic imaging
  • Sex Cord-Gonadal Stromal Tumors* / diagnostic imaging