Childhood Onset Pervasive Developmental Disorder

J Child Psychol Psychiatry. 1988 Mar;29(2):155-63. doi: 10.1111/j.1469-7610.1988.tb00700.x.


Two male children meeting criteria for Childhood Onset Pervasive Developmental Disorder (COPDD) are described. The current DSM-III category of COPDD may have value in separating these children from others with PDD. The authors suggest that these two children, and other children described in the literature as having dementia infantalis and/or disintegrative psychosis, have a distintegrative disorder resulting in muteness, profound mental retardation and severe autistic symptomatology. The term "pervasive disintegrative disorder" may be appropriate for such children and specific diagnostic criteria are suggested. The disorder appears to be extremely rare, with a prevalence estimate of 0.11 per 10,000.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Age Factors
  • Autistic Disorder / diagnosis
  • Child
  • Child Development Disorders, Pervasive / complications
  • Child Development Disorders, Pervasive / diagnosis*
  • Child, Preschool
  • Diagnosis, Differential
  • Humans
  • Intellectual Disability / complications
  • Male
  • Manuals as Topic / standards
  • Psychiatric Status Rating Scales
  • Psychotic Disorders / complications
  • Psychotic Disorders / diagnosis
  • Spasms, Infantile / complications
  • Terminology as Topic