Age of hypertension onset in multiple sclerosis patients

Farren Bs Briggs; Diane Krill; Eddie Hill; Devon S Conway

doi:10.1177/13524585211003016

Age of hypertension onset in multiple sclerosis patients

Mult Scler. 2021 Nov;27(13):2108-2111. doi: 10.1177/13524585211003016. Epub 2021 Mar 18.

Authors

Farren Bs Briggs¹, Diane Krill², Eddie Hill³, Devon S Conway⁴

Affiliations

¹ Neuroimmunological Disorders Gene-Environment Epidemiology Lab, Department of Population and Quantitative Health Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
² Department of Biological Sciences, Point Park University, Pittsburgh, PA, USA.
³ Department of Medicine, School of Medicine, University of California San Diego, La Jolla, CA, USA.
⁴ Mellen Center for Multiple Sclerosis Treatment and Research, Cleveland Clinic Foundation, Cleveland, OH, USA.

PMID: 33733922
DOI: 10.1177/13524585211003016

Abstract

Background/objective: Hypertension (HTN) is common in multiple sclerosis (MS), and it is associated with poorer outcomes. We sought to characterize HTN age at onset (AAO) by MS status.

Methods/results: There were 130,050 incident HTN patients, among whom there were 892 MS patients. We conducted multivariable linear regression adjusting for patient attributes. Sex- and race-stratified models were conducted. HTN AAO did not differ in patients with and without MS (p = 0.17). Similar null associations were observed in the sex- and race-specific analyses.

Conclusion: While there are complex relationships between HTN and MS, there are no differences in HTN AAO by MS status.

Keywords: Multiple sclerosis; comorbidity; epidemiology; hypertension.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Humans
Hypertension* / epidemiology
Multiple Sclerosis* / epidemiology