Increased blood angiotensin converting enzyme 2 activity in critically ill COVID-19 patients

ERJ Open Res. 2021 Mar 15;7(1):00848-2020. doi: 10.1183/23120541.00848-2020. eCollection 2021 Jan.


Critically ill #COVID19 patients display markedly increased alternative angiotensin pathway activity compared to healthy controls, reflected by increased blood ACE2 levels as well as decreased angiotensin-II and enhanced angiotensin-1-7 formation