Vitrectomy for full thickness macular hole developed during the course of anti-VEGF treatment of type 1 neovascular AMD

Eur J Ophthalmol. 2022 Sep;32(5):NP5-NP8. doi: 10.1177/11206721211002123. Epub 2021 Mar 19.

Abstract

Purpose: To report a case of treatment of a full-thickness macular hole, which appeared after 10 months of anti-VEGF treatment in neovascular age related macular degeneration (nAMD).

Methods: The patient was diagnosed as type 1 nAMD. The coexisting vitreomacular traction caused a full thickness macular hole after 10 months of treatment.

Patients: A 68-year-old woman treated with anti VEGF.

Results: Vitrectomy with the temporal inverted ILM flap technique succeeded in closing the hole. Further anti-VEGF treatment followed.

Conclusion: FTMH is a rare complication or coexistence in nAMD. Vitrectomy and continuous anti-VEGF treatment might result in satisfactory anatomical and functional results.

Keywords: AMD; CNV; inverted ILM flap technique; macular hole; neovascular age related macular degeneration.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Angiogenesis Inhibitors / therapeutic use
  • Female
  • Humans
  • Retinal Perforations* / diagnosis
  • Retinal Perforations* / etiology
  • Retinal Perforations* / surgery
  • Retrospective Studies
  • Tomography, Optical Coherence
  • Vascular Endothelial Growth Factor A
  • Visual Acuity
  • Vitrectomy / methods
  • Wet Macular Degeneration* / diagnosis
  • Wet Macular Degeneration* / drug therapy
  • Wet Macular Degeneration* / surgery

Substances

  • Angiogenesis Inhibitors
  • Vascular Endothelial Growth Factor A