Thyroid function in postpartum psychosis: An exploratory study

Asia Pac Psychiatry. 2021 Jun;13(2):e12465. doi: 10.1111/appy.12465. Epub 2021 Mar 19.

Abstract

The study aimed to compare thyroid function between psychosis with postpartum onset (PPO), psychosis without postpartum onset (PWPO), and normal postpartum females (HC). Twenty women were recruited in each of the three groups. The PPO group had significantly greater psychopathology and shorter episodes compared to the PWPO group. The PPO group was found to have significantly greater right lobe volume than the other groups. The PPO group also had significantly higher FT4 levels than the HC group. We conclude that isolated increase in FT4 and thyroid lobe volumetric changes could be more specifically associated with psychosis of post-partum onset.

Keywords: postpartum psychosis; thyroid; ultrasonography.

MeSH terms

  • Female
  • Humans
  • Postpartum Period
  • Psychotic Disorders* / epidemiology
  • Puerperal Disorders* / diagnosis
  • Puerperal Disorders* / epidemiology
  • Thyroid Gland / diagnostic imaging