Biologics in the Treatment of Plantar Fasciitis

Clin Podiatr Med Surg. 2021 Apr;38(2):245-259. doi: 10.1016/j.cpm.2020.12.009. Epub 2021 Feb 13.

Abstract

Plantar fasciitis has been considered an acute inflammatory disorder. However, the local histologic findings represent a more chronic, degenerative state without inflammation. Patients may be stuck in a chronic state of cyclical inflammation leading to tissue degeneration, refractory symptoms, and disability. This idea process has influenced the treatment approach of some practitioners who have implemented the idea of regenerative medicine and use of biologic adjuvants in the treatment of plantar heel pain. Biologic therapies provide many different cellular components, growth factors, and proteins to restore normal tissue biology and are a useful adjunct in the treatment of recalcitrant plantar fasciitis.

Keywords: Biologics; Growth factors; Plantar fasciitis; Regenerative medicine; Stem cells.

Publication types

  • Review

MeSH terms

  • Anesthetics, Local / administration & dosage
  • Extracorporeal Shockwave Therapy
  • Fasciitis, Plantar / therapy*
  • Humans
  • Patient Selection
  • Platelet-Rich Plasma
  • Stem Cell Transplantation

Substances

  • Anesthetics, Local