The relationship between premorbid intelligence and symptoms of severe anorexia nervosa restricting type

Int J Med Sci. 2021 Feb 4;18(7):1566-1569. doi: 10.7150/ijms.53907. eCollection 2021.


The purposes of this study were as follows: to compare premorbid IQ with present IQ in patients with more severe anorexia nervosa restricting type (AN-R) and to investigate the relationship between decreasing IQ and symptoms in patients with severe AN-R. Twenty-two participants were recruited (12 were AN-R patients; 10 were healthy controls). The average BMI in AN-R patients and healthy controls was 12.65 and 19.82, respectively. We assessed the outcomes using the Wechsler Adult Intelligence Scale-Third Edition (WAIS-III), the Japanese Adult Reading Test, The Eating Disorders Inventory-2 (EDI-2), Beck Depression Scale-2 (BDI-2) and State-Trait Anxiety Index. In two-way ANOVA, there were significant interactions for the FIQ and PIQ. Only in the AN-R group, a significant single main effect of time was evidenced for the FIQ and PIQ. In the AN-R group, a significantly high positive correlation was found between changes in the PIQ and the body dissatisfaction subscale of the EDI-2. These findings raise the possibility that in patients with severe AN-R, an excessive decrease in body weight induces decreased PIQ; as a result, they have worse dissatisfaction with their body shape.

Keywords: anorexia nervosa; premorbid intelligence.

Publication types

  • Comparative Study
  • Observational Study

MeSH terms

  • Adult
  • Anorexia Nervosa / complications
  • Anorexia Nervosa / diagnosis*
  • Anorexia Nervosa / psychology
  • Body Weight / physiology*
  • Cognitive Dysfunction / diagnosis*
  • Cognitive Dysfunction / etiology
  • Cognitive Dysfunction / psychology
  • Humans
  • Intelligence / physiology*
  • Intelligence Tests / statistics & numerical data
  • Middle Aged
  • Self Report
  • Severity of Illness Index*
  • Young Adult