Understanding oral mucositis and the principles of effective mouth care

Nurs Stand. 2021 Mar 22. doi: 10.7748/ns.2021.e11717. Online ahead of print.

Abstract

Mucositis involves an inflammation of the oral or gastrointestinal mucosa and is a common complication of cancer treatment. Mucositis is usually associated with high-dose chemotherapy, radiotherapy and, more recently, molecular targeted therapy. Oral mucositis refers specifically to inflammation and ulceration that occurs in the mouth. If not treated promptly, it can potentially lead to life-threatening infection requiring hospitalisation and intravenous antibiotics. This article discusses the causes and nursing management of oral mucositis, with an emphasis on self-care and optimal oral hygiene, as well as pharmacological interventions.

Keywords: cancer; cancer treatments; chemotherapy; clinical; gastrointestinal; immunotherapy; oncology; radiotherapy; targeted therapies.