Hair Follicle Chemosensation: TRPM5 Signaling Is Required for Anagen Maintenance

J Invest Dermatol. 2021 Sep;141(9):2300-2303. doi: 10.1016/j.jid.2021.02.747. Epub 2021 Mar 24.
No abstract available

Publication types

  • Letter

MeSH terms

  • Cell Proliferation
  • Cells, Cultured
  • Gene Expression Regulation
  • Gene Knockdown Techniques
  • Hair / metabolism*
  • Hair Follicle / metabolism*
  • Healthy Volunteers
  • Humans
  • Insulin-Like Growth Factor I / genetics
  • Keratinocytes / physiology*
  • Male
  • Organogenesis
  • Scalp / cytology*
  • Signal Transduction
  • TRPM Cation Channels / genetics
  • TRPM Cation Channels / metabolism*
  • Transforming Growth Factor beta2 / genetics

Substances

  • IGF1 protein, human
  • TGFB2 protein, human
  • TRPM Cation Channels
  • TRPM5 protein, human
  • Transforming Growth Factor beta2
  • Insulin-Like Growth Factor I