Acute respiratory effects of short-term exposures to nitrogen dioxide

Arch Environ Health. Mar-Apr 1988;43(2):138-42. doi: 10.1080/00039896.1988.9935842.


Eleven study subjects with asthma and 12 normal controls were monitored for 5 days with a portable continuous nitrogen dioxide (NO2) monitoring instrument held at breathing level before, during, and after cooking dinner on a gas cooking range. Forced expiratory volume in 1 sec (FEV1.0), forced expiratory volume (FEV25-75), peak expiratory flow, and a tracing of the entire flow curve was monitored before the gas stove was turned on, during a break in cooking, immediately after, and 1 hr after cooking was completed. Study design for detection of health effects of the acute exposures to NO2 described above and a method of validating findings in an exposure chamber are discussed in this paper.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adult
  • Air Pollutants / toxicity*
  • Asthma / physiopathology
  • Child
  • Cooking
  • Gases / toxicity
  • Humans
  • Lung Volume Measurements
  • Nitrogen Dioxide / toxicity*
  • Respiration / drug effects*
  • Spirometry


  • Air Pollutants
  • Gases
  • Nitrogen Dioxide