Successful Therapy With Ticagrelor in Three-Vessel Stent Thrombosis Related to Clopidogrel Resistance

Seung-Yul Lee; Jae Young Cho; Kyeong Ho Yun; Seok Kyu Oh

doi:10.1016/j.cjca.2021.03.017

Successful Therapy With Ticagrelor in Three-Vessel Stent Thrombosis Related to Clopidogrel Resistance

Can J Cardiol. 2021 Aug;37(8):1278-1280. doi: 10.1016/j.cjca.2021.03.017. Epub 2021 Mar 26.

Authors

Seung-Yul Lee¹, Jae Young Cho², Kyeong Ho Yun², Seok Kyu Oh²

Affiliations

¹ Regional Cardiocerebrovascular Center, Wonkwang University Hospital, Iksan, Korea. Electronic address: seungyul79@gmail.com.
² Regional Cardiocerebrovascular Center, Wonkwang University Hospital, Iksan, Korea.

PMID: 33775877
DOI: 10.1016/j.cjca.2021.03.017

Abstract

A 65-year-old man developed 3-vessel stent thrombosis after percutaneous coronary intervention with aspirin and clopidogrel. Platelet tests revealed clopidogrel resistance, which resolved after changing clopidogrel to ticagrelor. Although routine platelet tests after stenting are not recommended, these tests may be considered to identify the cause of stent thrombosis and modify antiplatelet therapy.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Aged
Aspirin / therapeutic use
Clopidogrel / adverse effects*
Coronary Angiography
Dual Anti-Platelet Therapy
Humans
Male
Percutaneous Coronary Intervention
Platelet Aggregation Inhibitors / administration & dosage*
Platelet Aggregation Inhibitors / adverse effects
Stents / adverse effects*
Thrombosis / diagnostic imaging
Thrombosis / drug therapy*
Ticagrelor / therapeutic use*

Substances

Platelet Aggregation Inhibitors
Clopidogrel
Ticagrelor
Aspirin