Chromosome sublocalization of a cDNA for human DNA polymerase-beta to 8p11----p12

Cytogenet Cell Genet. 1988;47(3):121-4. doi: 10.1159/000132527.

Abstract

We have localized a cDNA fragment that codes for human DNA polymerase-beta. Using somatic cell and in situ hybridization techniques, this cDNA was cloned by screening a human KM-3 cell cDNA library in lambda gt 11 for expression of fused beta-galactosidase-human DNA polymerase-beta proteins. We have mapped this human polymerase-beta gene to the short arm of chromosome 8 in the subregion 8p11----p12.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Chromosome Banding
  • Chromosome Mapping*
  • Chromosomes, Human, Pair 8*
  • DNA / genetics*
  • DNA Polymerase I / genetics*
  • Humans
  • Hybrid Cells
  • Karyotyping
  • Mice
  • Nucleic Acid Hybridization

Substances

  • DNA
  • DNA Polymerase I