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. 2021 Apr 24;85(5):1290-1293.
doi: 10.1093/bbb/zbab021.

Dihydropyriculol produced by Pyricularia oryzae inhibits the growth of Streptomyces griseus

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Dihydropyriculol produced by Pyricularia oryzae inhibits the growth of Streptomyces griseus

Yuuki Furuyama et al. Biosci Biotechnol Biochem. .

Abstract

Dihydropyriculol is a major secondary metabolite of Pyricularia oryzae. However, the biological activity of dihydropyriculol has not been reported. Here, we showed that dihydropyriculol has inhibitory activity against Streptomyces griseus. Localization analysis of dihydropyriculol revealed that dihydropyriculol could reach to S. griseus under confrontation culture. These results suggest that dihydropyriculol can be used as a chemical weapon against S. griseus.

Keywords: Pyricularia oryzae; chemical interaction; dihydropyriculol; natural products.

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