Myoedema with pseudohypertrophic hypothyroid myopathy (Hoffman's syndrome)

Pract Neurol. 2021 Aug;21(4):360-362. doi: 10.1136/practneurol-2020-002898. Epub 2021 Mar 30.

Abstract

Myoedema is an under-recognised neurological sign that can help the bedside diagnosis of metabolic or endocrine myopathies. Myoedema together with pseudo-hypertrophy make a likely diagnosis of hypothyroid myopathy, and its identification may avoid unnecessary investigations.

Keywords: muscular dystrophy; myopathy; neuroendocrinology.

MeSH terms

  • Congenital Hypothyroidism*
  • Humans
  • Hypertrophy
  • Muscle, Skeletal
  • Muscular Diseases* / complications
  • Muscular Diseases* / diagnosis
  • Syndrome