An uncommon case of vulvar cancer metastatic to breast

Exp Oncol. 2021 Mar;43(1):92-95. doi: 10.32471/exp-oncology.2312-8852.vol-43-no-1.15843.


Vulvar carcinoma corresponds to the fourth gynecological malignancy in incidence, with more than forty thousand new cases being estimated worldwide in 2020. It is a disease characterized by locoregional spread presenting high recurrence rates although distant metastases are an uncommon event. The purpose of this work is to describe the diagnosis, treatment, and clinical course of vulvar carcinoma in a patient who presented regional recurrences and late metastasis to the mammary gland. Vulvar cancer is a disease with a well-defined natural history; but with the advancement of therapeutic possibilities in recent years, it has been possible to improve the prognosis, reducing the chance of locoregional recurrence. Thus, the possibility of distance recurrence must be remembered in inpatient follow-up with locally advanced vulvar carcinoma, even if atypically, as in the case reported.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Breast Neoplasms / secondary*
  • Carcinoma, Squamous Cell / secondary*
  • Female
  • Humans
  • Vulvar Neoplasms / pathology*