Effect of auricular point pressing therapy on hyperplasia of mammary glands: A protocol for systematic review and meta-analysis

Medicine (Baltimore). 2021 Apr 2;100(13):e24875. doi: 10.1097/MD.0000000000024875.


Background: In recent years, with the accelerated pace of life, diet, environmental problems occur frequently. External factors are easily to cause endocrine disorders and hormone sensitivity of breast tissue, which can lead to mammary hyperplasia. The incidence rate of hyperplasia of mammary glands is increasing year by year, and the age of onset is also getting lower and lower. If not treated in time, there is a crisis of breast cancer.Clinical studies have found that auricular point pressing therapy is widely used in clinical treatment of mammary hyperplasia recently, but the efficacy of massage in the treatment of mammary hyperplasia has not been systematically reviewed. The purpose of this study is to explore the efficacy, safety and effectiveness of auricular point pressing therapy in the treatment of hyperplasia of mammary glands.

Methods: We will search PubMed, Web of Science, Cochrane Library, EMBASE, Wan fang Database, Chinese Scientific Journal Database, CNKI, VIP, and Chinese Biomedical Literature Database. The retrieval date was January 10, 2021. RevMan 5.3 software was used to evaluate the quality and risk of included studies. The efficacy, recurrence rate, and symptom score of breast hyperplasia were analyzed, and the results were observed and measured.

Results: This study will be from the clinical efficiency, improvement rate, pain symptoms disappear rate, tumor size improvement rate, and other aspects of the existing evidence for a high quality synthesis, as well as auricular point pressing therapy adverse events.

Conclusion: the conclusion of this review will provide the basis for judging whether auricular point pressing therapy is safe and effective in the treatment of hyperplasia of mammary glands.

Ethics and dissemination: This systematic will evaluate the effectiveness and safety of auricular point pressing therapy in the treatment of hyperplasia of mammary glands. As all data used in this systematic review and meta-analysis have been published, ethical approval is not required for this review.

Protocol registration number: INPLASY202110028.

MeSH terms

  • Acupuncture Points*
  • Breast Diseases / pathology
  • Breast Diseases / therapy*
  • Clinical Trials as Topic
  • Ear Auricle
  • Female
  • Humans
  • Hyperplasia / therapy
  • Mammary Glands, Human / pathology*
  • Massage / methods*
  • Meta-Analysis as Topic
  • Research Design
  • Systematic Reviews as Topic
  • Treatment Outcome