Current Oncologic Standards for Surgery of Small Bowel Cancers

J Gastrointest Cancer. 2022 Jun;53(2):434-438. doi: 10.1007/s12029-021-00635-9. Epub 2021 Mar 31.

Abstract

Purpose: The last 2 decades has witnessed efforts towards standardization of surgery for small bowel cancers. The proposed recent guidelines/recommendations pertaining to choice of procedure and extent of lymphadenectomy are based on analysis of data from high volume centres of excellence. We evaluated whether these recently proposed oncologic recommendations can be replicated in the setting of single centre/team.

Methods: This was a retrospective analysis of consecutive adult patients (age ≥ 18 years) who underwent surgery for tumours of small intestine (duodenum, jejunum, and ileum) by the same team of surgeons from 01/01/2010 to 12/31/2019. The procedure performed and lymph nodes harvested during pathologic examination were compared with recent recommendations.

Results: Of the 32 patients (20 males and 12 females), mean age was 52.4 (range 31-77) years. Twenty-nine (90.6%) patients underwent surgery for small bowel cancers. Duodenum was the most common site, while NET was the commonest cancer. Whipple's procedure was performed for tumours of II part of duodenum, while for the rest, segmental resection was performed. The median number of lymph nodes examined for duodenal adenocarcinoma and NET was 14 and 9, respectively. For jejunal/ileal adenocarcinoma, median lymph node number examined was 11.

Conclusion: Our study shows that these recently proposed standards for surgery of small bowel cancers are achievable if basic principles of oncologic surgery are followed.

Keywords: Adenocarcinoma; Gastrointestinal stromal tumours; Intestine small; Neuroendocrine tumours; Surgery.

MeSH terms

  • Adenocarcinoma* / pathology
  • Adenocarcinoma* / surgery
  • Adolescent
  • Adult
  • Aged
  • Duodenal Neoplasms* / pathology
  • Duodenal Neoplasms* / surgery
  • Female
  • Humans
  • Ileal Neoplasms* / pathology
  • Intestine, Small / pathology
  • Intestine, Small / surgery
  • Jejunal Neoplasms* / pathology
  • Jejunal Neoplasms* / surgery
  • Male
  • Middle Aged
  • Reference Standards
  • Retrospective Studies