Strengths and challenges of longitudinal non-human primate neuroimaging

Neuroimage. 2021 Aug 1:236:118009. doi: 10.1016/j.neuroimage.2021.118009. Epub 2021 Mar 29.

Abstract

Longitudinal non-human primate neuroimaging has the potential to greatly enhance our understanding of primate brain structure and function. Here we describe its specific strengths, compared to both cross-sectional non-human primate neuroimaging and longitudinal human neuroimaging, but also its associated challenges. We elaborate on factors guiding the use of different analytical tools, subject-specific versus age-specific templates for analyses, and issues related to statistical power.

Keywords: Ageing; Development; Magnetic resonance imaging; Non-human primate; Simulation; Templates.

Publication types

  • Research Support, N.I.H., Intramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aging*
  • Animals
  • Cross-Sectional Studies
  • Diffusion Tensor Imaging / methods
  • Diffusion Tensor Imaging / standards
  • Functional Neuroimaging / methods
  • Functional Neuroimaging / standards
  • Human Development*
  • Humans
  • Longitudinal Studies
  • Magnetic Resonance Imaging
  • Neuroimaging* / methods
  • Neuroimaging* / standards
  • Primates*