Study of Two Constraints Impacting Measurements of Human Glycemia Using a Microwave Sensor

Biosensors (Basel). 2021 Mar 15;11(3):83. doi: 10.3390/bios11030083.

Abstract

The measurement of glycemia is impacted by several constraints; those constraints have to be identified and quantified when designing an electromagnetic noninvasive sensor. The second phase concerns the level of the influence of these constraints. In this work, we investigated the impact of vein radius located in the forearm on a resonant microwave sensor to measure glycemia. We performed a numerical simulation using COMSOL Multiphysics of a proposed tissue model that was in contact with a microwave resonator. Some other factors affect the measurement, such as temperature, perfusion, sensor positioning and motion, tissue heterogeneity, and other biological activity. The sensor must be robust to the above-mentioned constraints. Because vein size changes from one person to another, the dielectric properties seen by the sensor will be different. This has been demonstrated by the change created in the resonance frequency of the simulated sensor for different vein sizes. The second constraint that was assessed is the dosimetry. The specific absorption rate (SAR) of any electromagnetic device should be evaluated and compared with SAR limits in the safety standards to ensure the safety of the user. Simulation results are in good agreement with SAR limits in the safety standards.

Keywords: SAR; diabetics; glycemia; microwave sensor; tissue properties; vein.

MeSH terms

  • Biosensing Techniques*
  • Blood Glucose / analysis*
  • Computer Simulation
  • Humans
  • Microwaves*
  • Temperature
  • Veins / anatomy & histology*

Substances

  • Blood Glucose